孙慧(广大教授)

时间:2024-01-02 11:18:01编辑:小蔡

孙慧(广大教授)的个人简介

孙慧,女,广州大学环境科学与工程学院教授。长期从事MIPs技术、毛细管电泳、微流控芯片实验室系统、化学/生物传感器及液/气相色谱技术在环境、食品和生物医学检测中的应用研究工作。

简历

1994年于武汉大学环境科学系获学士学位,2002年7月于南开大学化学系获硕士学位,2006年8月于香港大学化学系获博士学位;2006年9月至2008年8月于香港大学化学系任协作研究员,2008年8月-2010年12月于香港大学做博士后研究。

成就

孙慧曾主持香港大学博士后基金一项,作为主要研究人员,参与多项香港特别行政区创新科技基金、广东-香港技术合作基金、香港大学基础研究种子基金以及香港大学应用研究种子基金的科研工作。特别是2006年8月至2010年12月在香港大学做协作研究员和博士后研究期间,完成了香港特别行政区创新科技基金(ITS/108/06)项目,开发研制出了用于检测/鉴别食品、饮料中致味物质的“电子舌”微流控系统,该研究成果参加香港科技展览时,受到香港媒体的广泛关注,正申请美国专利。同时,主持完成了一项香港大学基金项目:基于分子印迹和微流控技术的压电传感器在环境和临床医学中的应用。参加国际会议20次,做口头报告5次,曾参与Encyclopedia of Sensors 著作编写,并在Biosens. Bioelectro., Electrophoresis,J. Chromatogr. A,Analyst,Sens. Actuat. B, Anal. Chim. Acta, Encyclop. Sens., Chem. Sens.等杂志上发表研究性论文近30篇。

学术成果

科研项目

曾主持国家自然科学基金2项,教育部重点科学技术1项,广东省自然科学基金1项,广州市科技计划项目1项,香港大学博士后基金1项。

基于离子印迹与识别的重金属离子荧光光纤传感器的研究(国家基金,21477026,2015-2018,主持)基于分子印迹微流控CE系统的空气羰基化合物分析的研究(国家基金,21107018,2012-2014,主持)空气中微量气、固态醛酮化合物测定的芯片技术研究(教育部科学技术研究重点项目,212129,2012-2015,主持)大气PM2.5中羰基化合物的分子识别及微流控芯片监测系统研究(广东省自然科学基金项目,2014A030313525,2015-2017,主持)雾霾中醛酮类污染物的快速检测系统研究(广州市科技计划项目201504291741356,2016-2019,主持)基于分子印迹和微流控技术的压电传感器在环境和临床中的应用研究(香港大学博士后基金项目, 200807176235,2009-2010,主持)抗生素分子印迹光子晶体光纤传感器阵列的设计、构建及其应用研究(国家基金,21677053,2017-2020,参与)基于离子识别和光纤传导的重金属离子荧光传感器的关键敏感元件研究(广东省普通高校特色创新项目,2015-2017,参与)城市湖泊水体微表层种短链氯化石蜡的富集特征及其影响因素研究(广东省自然科学基金项目,2016A030310264,2016-2019,参与)量子点协同激光诱导荧光测定蛋白和肽生物标记物的微流控芯片毛细管电泳研究(香港大学基础研究种子基金,201111159206,2012-2014,参与)基于微流控芯片-毛细管电泳技术以及非指数富集核酸适配体筛选技术的压电石英晶体传感器在病原性蛋白标记物中测定中的应用研究(香港综合研究基金,HKU702210P,2010-2013,参与)微电极-微流控芯片毛细管电泳装置测定未标记核酸(香港大学基础研究种子基金,201011159211,2011-2013,参与)基于微流控芯片-毛细管电泳技术以及非指数富集核酸适配体筛选技术的压电石英晶体传感器在测定病原性蛋白标记物中的应用研究(香港大学基础研究种子基金,200911159175,2010-2012,参与)基于微流控芯片-毛细管电泳通道内微电极进行原位测定具有重要生物医学意义的分子(香港大学基础研究种子基金,200811159134,2009-2011,参与)压电-DNA生物传感器系统在细菌测定中的应用研究(香港大学应用研究种子基金,200802160019,2008-2009,参与)基于分子印迹识别和石英微天平传感器的“电子舌”技术研究(香港特别行政区创新科技基金,ITS/108/06,2006- 2007,参与)代表性论文

(1)Hui Sun, Jiaping Lai, Dongsheng Lin, Xuexia Huang, Yunling Li, A novel fluorescent multi- functional monomer for preparation of silver ion-imprinted fluorescent on-off chemosensor. Sens. Actuat. B, 2016, 224: 485-491.(SCI影响因子5.401)

(2)Hui Sun, Jiaping Lai, Fang Chen, Derong Zhu. Molecularly imprinted microspheres synthesized by a simple, fast and universal suspension polymerization for selective extraction of topical anesthetics benzocaine in human serum and fish tissues. Anal. Bioanal. Chem., 2015, 407: 1745-1752.(SCI影响因子3.431)

(3)Hui Sun, Jiaping Lai, Yingsing Fung, Simultaneous determination of gaseous and particulate ambient carbonyls by coupling micellar electrokinetic capillary chromatography with molecular imprinting solid-phase extraction. J. Chromatogr. A, 2014, 1358: 303-308.(SCI影响因子3.981)

(4)Hui Sun,Kwokman Lau, Yingsing Fung, A new capillary electrophoreSis buffer for determining organic and inorganic anions in electroplating bath with surfactant additives, J. Chromatogr. A, 2010, 1217: 3244-3250.(SCI影响因子3.981)

(5)Hui Sun,Zhou Nie, Yingsing Fung. Determination of free bilirubin and its binding capacity by HSA using a microfluidic chip-capillary electrophoresis device with a multi-segment circular-ferro fluid-driven micromixing injection. Electro- phoresis, 2010, 31(18): 3061-3069.(SCI影响因子2.744)

(6)Hui Sun,Yingsing Fung. DNA biosensor based on quartz crystal microbalance and polymerase chain reaction for detecting E. Coli. in environmental water. Biosens. Bioelectron., 2009, 24:1405-1411.(SCI影响因子7.780)

(7)Hui Sun,Kingyee Chan, Yingsing Fung. Determination of gaseous and particulate carbonyls in air by gradient-elution micellar electrokinetic capillary chromatography. Electrophoresis, 2008, 29: 3971-3979.(SCI影响因子2.744)

(8)Hui Sun,Zhihong Mo, Jacqueline T. S. Choy, Derong Zhu,Yingsing Fung. Development of piezoelectric quartz crystal sensor array for sensing taste-causing compounds in food. Sens. Actuat. B, 2008, 131: 148-158.(SCI影响因子5.401)

(9)Hui Sun,Yingsing Fung,Flowanalysis coupled with PQC/DNA biosensor for assay of E. coli based on detecting DNA products from PCR amplification.Biosens. Bioelectron.,2006, 22: 506-512. (SCI影响因子7.780)

(10)Hui Sun,Yingsing Fung.Piezoelectric quartz crystal sensor for rapid analysis of pirimicarb residues using molecularly imprinted polymers as recognition elements. Anal. Chim. Acta, 2006, 576: 67-76. (SCI影响因子4.950)

(11)Hui Sun,Youyu Zhang, Shihui Si, Derong Zhu,Yingsing Fung.Piezoelectric quartz crystal (PQC) with photochemically deposited nano-sized Ag particles for determining cyanide at trace levels in water. Sens. Actuat. B-Chem.2005, 108: 925-932.(SCI影响因子5.401)

(12)Hui Sun, Shihui Si, Youyu Zhang, Derong Zhu, Yingsing Fung. Piezoelectric quartz crystal (PQC) with photochemically deposited nano-sized Ag particles for determining cyanide at trace levels in water. Chem. Sens.2004,20: 500-501.

(13)Yunling Li,Hui Sun*, Jiaping Lai*, Xiangyang Chang, Ping Zhang, Shili Chen Determination of carbonyl pollutants adsorbed on ambient particulate matter of type PM2.5 by using magnetic molecularly imprinted microspheres for sample pretreatment and capillary electrophoresis for separation and quantitation, Microchimica Acta 2018, 185 (2):122-134. (SCI影响因子4.580)

(14) Yanhui He, Jiaping Lai*,Hui Sun*, Zhiming Chen, Sheng Lan. A fast, sensitive and stable fluorescent fiber-optic chemosensor for quantitative detection of Fein real water and HepG2 living cells. Sens. Actuat. B, 2016, 225:405-412. (SCI影响因子5.401)

(15) Shan FS, Lai JP*, Sun H, Zhang P, Luo C, He YH, Feng HR. A facile, fast responsive and highly selective mercury(II) probe characterized by the fluorescence quenching of 2,9-dimethyl-1,10-phenanthroline and two new metal-organic frameworks. RSC Advances, 2016, 6, 66215-66223. (SCI影响因子3.108)

(16) Jiaping Lai, Yue Zuo,Hui Sun*, Ying Yu. Hydrophilic molecularly imprinted microspheres functionalized with amino and carboxyl groups for highly selective recognition of human hemoglobin in aqueous solution,RSC Advances,2015,5(63):51392-51398.

(17) Jiaping Lai, Fang Chen,Hui Sun*, Li Fan, Yue Zuo. Molecularly imprinted microspheres for anti-cancer drug aminoglutethimide: synthesis, characteri- zation and solid-phase extraction application in human urine sample. J. Sep. Sci., 2014, 37:1170-1176. (SCI影响因子2.557)

(18) Dongsheng Lin, Jiaping Lai *,Hui Sun*, Zhou Yang, Yue Zuo. A turn-on fluorescein spirolactam derivative as a high selective fluorescence probe for detection of silver ion (I) in water. Anal. Methods, 2014, 6: 1517-1522. (SCI影响因子1.900)

(19) Jiaping Lai, Li Xie,Hui Sun*, Fang Chen. Synthesis and evaluation of molecularly imprinted polymeric microspheres for highly selective extraction of an anti-AIDS drug emtricitabine. Anal. Bioanal. Chem., 2013,405: 4269-4275. (SCI影响因子3.431)

(20)顾航,潘彦光,黄振坚,朱德荣,黄艳梅,曾青松,孙慧*.分子印迹光子晶体凝胶传感器检测食品中的防腐剂,分析测试学报,2017, 36(8): 1023-1028

(21)朱德荣,孙慧*,刘红菊,何明华.液相微萃取-气质联用法在增塑剂测定中的应用和对比,分析化学, 2013,41(10):1582-1586. (SCI影响因子0.795)

(22)赖家平,孙慧*,陈芳,樊莉,刘桂伶,林东升,杨洲.分子印迹微米微球的合成方法及在固相萃取中的应用研究进展,分析测试学报,2012, 31(9): 1161-1169.

(23)朱德荣,孙慧*,潘文龙,陈泳.纳米银修饰的压电晶体传感器用于水中痕量氰化物测定的研究,分析测试学报,2008, 27: 686-690.

专著

(1)Hui Sun, Yingsing Fung, (Chapter 6) sample cleanup and analyte enrichment -integrating MIP/SPE with ME/MC-CE device to enhance sample cleanup and multi-dimension analyte enrichment for hourly determination of atmospheric carbonyl compounds, Microfluidic Chip-Capillary Electrophoresis (MC-CE) Devices -Integrating techniques to achieve intended applications, CRC press, 2015

(2) Yingsing Fung, Youyu Zhang, Shihui Si,Hui Sunand Shouzhuo Yao, DNA Piezoelectric Quartz Crystal Biosensor, Encyclopedia of Sensors, American Scientific Publishers, CA, USA. 2006

专利

(1)Yingsing Fung,Hui Sun, Zhihong Mo, Derong Zhu, Jacqueline Tszshan Choy, Yinyee Lee, Electronic Tongue Sensor, 2011.9, US Patent, 8,004,152。

(2)赖家平,左悦,林东升,孙慧,何燕惠,一种荧光多功能单体及其合成方法与应用,发明专利,2015.4.30,中国,ZL 201510217322.6。

(3)冯应升;孙慧;莫志宏;朱德荣;蔡紫珊;李贤意.电子舌传感器,2013.4,中国, CN101836107A。

(4)陈永亨;张平;陈绮洁;姚焱;吴颖娟;黄雪夏;李祥平;孙慧.一种以铅锌矿冶炼废水为原料制备碘化亚铊的方法,2014,中国, CN103818947A。

(5)孙慧,李韵灵,常向阳2,4-二硝基苯胺磁性分子印迹复合材料的制备方法和应用,发明专利,中国,201610928664.3。

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